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Peptide libraries: from epitope mapping to in-depth high-throughput analysis
Trends in Pharmacological Sciences ( IF 13.9 ) Pub Date : 2024-05-08 , DOI: 10.1016/j.tips.2024.04.004
Debora Iaculli , Steven Ballet

Peptide arrays are a valuable instrument in the characterization of protein–protein interactions (PPIs) and immunogenic regions. New methods were developed to exploit the high-throughput potential of peptide arrays to obtain more in-depth information, replacing traditional resource-intensive experiments. Here, we discuss the recent advances in peptide-array-based technologies and the remaining challenges.



中文翻译:


肽库:从表位作图到深入的高通量分析



肽阵列是表征蛋白质-蛋白质相互作用 (PPI) 和免疫原性区域的重要工具。人们开发了新方法来利用肽阵列的高通量潜力来获取更深入的信息,取代传统的资源密集型实验。在这里,我们讨论基于肽阵列的技术的最新进展和剩余的挑战。

更新日期:2024-05-08
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