The representation of distinct spaces by hippocampal place cells has been linked to changes in their place fields (the locations in the environment where the place cells discharge strongly), a phenomenon that has been termed ‘remapping’. Remapping has been assumed to be accompanied by the reorganization of subsecond cofiring relationships among the place cells, potentially maximizing hippocampal information coding capacity. However, several observations challenge this standard view. For example, place cells exhibit mixed selectivity, encode non-positional variables, can have multiple place fields and exhibit unreliable discharge in fixed environments. Furthermore, recent evidence suggests that, when measured at subsecond timescales, the moment-to-moment cofiring of a pair of cells in one environment is remarkably similar in another environment, despite remapping. Here, I propose that remapping is a misnomer for the changes in place fields across environments and suggest instead that internally organized manifold representations of hippocampal activity are actively registered to different environments to enable navigation, promote memory and organize knowledge.

海马位置细胞对不同空间的表征与其位置场（位置细胞在环境中强烈放电的位置）的变化有关，这种现象被称为“重新映射”。重新映射被认为伴随着位置细胞之间亚秒级共燃关系的重组，从而可能最大化海马信息编码能力。然而，一些观察结果对这一标准观点提出了挑战。例如，位置单元表现出混合选择性、编码非位置变量、可以具有多个位置场并且在固定环境中表现出不可靠的放电。此外，最近的证据表明，当在亚秒时间尺度上测量时，尽管进行了重新映射，但在一个环境中一对细胞的即时共烧在另一种环境中非常相似。在这里，我认为重新映射是对跨环境的位置场变化的误称，并建议将海马活动的内部组织的多种表征主动注册到不同的环境中，以实现导航、促进记忆和组织知识。