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Branching out beyond canonical brown adipocyte function
Cell Metabolism ( IF 27.7 ) Pub Date : 2024-05-07 , DOI: 10.1016/j.cmet.2024.04.011 Helaina Von Bank 1 , Judith Simcox 2
中文翻译:
超越典型的棕色脂肪细胞功能
更新日期:2024-05-07
Cell Metabolism ( IF 27.7 ) Pub Date : 2024-05-07 , DOI: 10.1016/j.cmet.2024.04.011 Helaina Von Bank 1 , Judith Simcox 2
Affiliation
Brown adipose tissue has long been functionally characterized as an organ that regulates thermogenesis, body weight set point, and glucose homeostasis. In the May 9, 2024, issue of Cell, Verkerke et al. discover a novel function for brown adipose tissue in processing branched-chain amino acids into antioxidant metabolites that enter the circulation and regulate insulin signaling in the liver.
中文翻译:
超越典型的棕色脂肪细胞功能
棕色脂肪组织长期以来在功能上被认为是调节产热、体重设定点和葡萄糖稳态的器官。 Verkerke 等人在 2024 年 5 月 9 日发表的《Cell》杂志中。发现棕色脂肪组织将支链氨基酸加工成抗氧化代谢物的新功能,这些代谢物进入循环并调节肝脏中的胰岛素信号传导。