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A tale of two calcium channels: structural pharmacology of Cav2.1 and Cav3.2
Cell Research ( IF 28.1 ) Pub Date : 2024-05-03 , DOI: 10.1038/s41422-024-00961-0 Laurent Ferron 1 , Gerald W Zamponi 1
中文翻译：
两个钙通道的故事：Cav2.1 和 Cav3.2 的结构药理学
更新日期：2024-05-03
Cell Research ( IF 28.1 ) Pub Date : 2024-05-03 , DOI: 10.1038/s41422-024-00961-0 Laurent Ferron 1 , Gerald W Zamponi 1
Affiliation
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Voltage-gated calcium channels control a plethora of physiological and pathophysiological processes and are important targets for therapeutic intervention into conditions such as epilepsy, pain, and cardiovascular diseases. Two elegant studies published in Cell Research provide structural insights into the molecular pharmacology of P/Q-type and T-type calcium channels.
中文翻译：
两个钙通道的故事：Cav2.1 和 Cav3.2 的结构药理学
电压门控钙通道控制着大量的生理和病理生理过程，是治疗干预癫痫、疼痛和心血管疾病等疾病的重要靶标。发表在Cell Research 上的两项出色的研究为 P/Q 型和 T 型钙通道的分子药理学提供了结构见解。
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