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Controversies in orthopaedic oncology.
The Bone & Joint Journal ( IF 4.9 ) Pub Date : 2024-05-01 , DOI: 10.1302/0301-620x.106b5.bjj-2023-1381
Lee M. Jeys 1 , Joachim Thorkildsen 2 , Vineet Kurisunkal 1 , Ajay Puri 3 , Pietro Ruggieri 4 , Matthew T. Houdek 5 , Richard A. Boyle 6 , Walid Ebeid 7 , Eduardo Botello 8 , Guy V. Morris 1 , Minna K. Laitinen 9
Affiliation  

Chondrosarcoma is the second most common surgically treated primary bone sarcoma. Despite a large number of scientific papers in the literature, there is still significant controversy about diagnostics, treatment of the primary tumour, subtypes, and complications. Therefore, consensus on its day-to-day treatment decisions is needed. In January 2024, the Birmingham Orthopaedic Oncology Meeting (BOOM) attempted to gain global consensus from 300 delegates from over 50 countries. The meeting focused on these critical areas and aimed to generate consensus statements based on evidence amalgamation and expert opinion from diverse geographical regions. In parallel, periprosthetic joint infection (PJI) in oncological reconstructions poses unique challenges due to factors such as adjuvant treatments, large exposures, and the complexity of surgery. The meeting debated two-stage revisions, antibiotic prophylaxis, managing acute PJI in patients undergoing chemotherapy, and defining the best strategies for wound management and allograft reconstruction. The objectives of the meeting extended beyond resolving immediate controversies. It sought to foster global collaboration among specialists attending the meeting, and to encourage future research projects to address unsolved dilemmas. By highlighting areas of disagreement and promoting collaborative research endeavours, this initiative aims to enhance treatment standards and potentially improve outcomes for patients globally. This paper sets out some of the controversies and questions that were debated in the meeting.

中文翻译:


骨科肿瘤学的争议。



软骨肉瘤是第二常见的手术治疗原发性骨肉瘤。尽管文献中有大量科学论文,但关于原发肿瘤的诊断、治疗、亚型和并发症仍然存在重大争议。因此,需要就日常治疗决策达成共识。 2024 年 1 月,伯明翰骨科肿瘤学会议 (BOOM) 试图获得来自 50 多个国家的 300 名代表的全球共识。会议重点讨论了这些关键领域,旨在根据来自不同地理区域的证据合并和专家意见达成共识声明。与此同时,由于辅助治疗、大量暴露和手术复杂性等因素,肿瘤重建中的假体周围关节感染(PJI)提出了独特的挑战。会议讨论了两阶段修订、抗生素预防、化疗患者急性 PJI 的处理,以及确定伤口处理和同种异体移植重建的最佳策略。会议的目标不仅仅是解决眼前的争议。它寻求促进与会专家之间的全球合作,并鼓励未来的研究项目来解决未解决的困境。通过强调分歧领域和促进合作研究努力,该倡议旨在提高治疗标准并可能改善全球患者的治疗结果。本文列出了会议中争论的一些争议和问题。
更新日期:2024-05-01
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