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Ring-Opening Coupling of Cyclopropanol with 1,2,3-Triazole for the Synthesis of Fused Triazoles
Organic Letters ( IF 4.9 ) Pub Date : 2024-05-02 , DOI: 10.1021/acs.orglett.4c00702 Yi Wu 1 , Hu Zhang 2 , Qi Wang 2 , Peng Tang 2 , Dan Jiang 2 , Jiahong Mo 2 , Hanyue Qiu 2 , Ling He 2 , Min Zhang 1, 2
Organic Letters ( IF 4.9 ) Pub Date : 2024-05-02 , DOI: 10.1021/acs.orglett.4c00702 Yi Wu 1 , Hu Zhang 2 , Qi Wang 2 , Peng Tang 2 , Dan Jiang 2 , Jiahong Mo 2 , Hanyue Qiu 2 , Ling He 2 , Min Zhang 1, 2
Affiliation
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A radical ring-opening arylation of cyclopropanol with 1,2,3-triazole has been achieved. This synthetic protocol provides straightforward access to a wide range of structurally diverse and chiral 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyridines with high efficiency from readily available chiral cyclopropanols.
中文翻译：
环丙醇与 1,2,3-三唑开环偶联合成稠合三唑
已经实现了环丙醇与1,2,3-三唑的自由基开环芳基化。该合成方案可以直接从容易获得的手性环丙醇中高效地获得各种结构多样的手性 4,5,6,7-四氢[1,2,3]三唑并[1,5- a ]吡啶。
更新日期：2024-05-02
中文翻译：
环丙醇与 1,2,3-三唑开环偶联合成稠合三唑
已经实现了环丙醇与1,2,3-三唑的自由基开环芳基化。该合成方案可以直接从容易获得的手性环丙醇中高效地获得各种结构多样的手性 4,5,6,7-四氢[1,2,3]三唑并[1,5- a ]吡啶。
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