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Programmable spin and transport of a living shrimp egg through photoacoustic pressure
Optics Letters ( IF 3.1 ) Pub Date : 2024-04-23 , DOI: 10.1364/ol.518231
Xichuan Zhao , Ruoqin Zhang , Jinzhi Li , Di Zhou , Feng Li , Honglian Guo

In the fields of biomedicine and microfluidics, the non-contact capture, manipulation, and spin of micro-particles hold great importance. In this study, we propose a programmable non-contact manipulation technique that utilizes photoacoustic effect to spin and transport living shrimp eggs. By directing a modulated pulsed laser toward a liquid-covered stainless-steel membrane, we can excite patterned Lamb waves within the membrane. These Lamb waves occur at the interface between the membrane and the liquid, enabling the manipulation of nearby particles. Experimental results demonstrate the successful capture, spin, and transport of shrimp eggs in diameter of 220 µm over a distance of about 5 mm. Calculations indicate that the acoustic radiation force and torque generated by our photoacoustic manipulation system are more than 299.5 nN and 41.0 nN·mm, respectively. The system surpasses traditional optical tweezers in terms of force and traditional acoustic tweezers in terms of flexibility. Consequently, this non-contact manipulation system significantly expands the possibilities for applications in various fields, including embryo screening, cell manipulation, and microfluidics.

中文翻译:

通过光声压力对活虾卵进行可编程旋转和运输

在生物医学和微流控领域,微粒子的非接触捕获、操纵和旋转具有非常重要的意义。在这项研究中,我们提出了一种可编程的非接触式操纵技术,利用光声效应来旋转和运输活虾卵。通过将调制脉冲激光引导至液体覆盖的不锈钢膜,我们可以在膜内激发图案化的兰姆波。这些兰姆波发生在膜和液体之间的界面,从而能够操纵附近的粒子。实验结果表明,成功捕获、旋转并在约 5 毫米的距离内运输直径 220 微米的虾卵。计算表明,我们的光声操纵系统产生的声辐射力和扭矩分别超过299.5 nN和41.0 nN·mm。该系统在力方面优于传统光镊,在灵活性方面优于传统声镊。因此,这种非接触式操纵系统显着扩展了在胚胎筛选、细胞操纵和微流体等各个领域的应用可能性。
更新日期:2024-04-24
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