Mimicking enzymes’ ability to orient substrates through nanoconfinement holds significant promise for the development of artificial catalysts with enhanced performance. Recently in Chem, a cyclodextrin-based metal-organic framework has been shown to undergo selective C–H bond activation in the presence of guest molecules upon photoirradiation, illustrating a crucial advance in replicating biological catalysis within artificial matrices.

中文翻译：

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通过框架限制实现高度位点选择性的 C(sp3)–H 键功能化

模仿酶通过纳米限制定向底物的能力为开发具有增强性能的人造催化剂带来了巨大的希望。最近，在《Chem》杂志上，基于环糊精的金属有机框架已被证明在客体分子存在的情况下在光照射下会发生选择性 C-H 键活化，这说明了在人造基质中复制生物催化的关键进展。