Glycerol esterification produces a variety of valuable chemicals and has been a subject of great interest in recent years. Lipase-catalysed synthesis of acylglycerols reactions have many potential applications, including in the production of structured lipids, biofuels and pharmaceuticals. It offers several benefits over traditional chemical methods, including higher selectivity, milder reaction conditions and increased sustainability. In this systematic review, we summarize 52 primary research of lipase catalysed synthesis of acylglycerol published from 2012 to 2022. Different types of reactions employed in the synthesis of acylglycerols using various lipases are thoroughly discussed. The use of lipase in as biocatalyst in the synthesis of acylglycerols is safe for consumption and sustainable as it can reduce the utilization of toxic and hazardous organic solvents and chemicals that cause harm to human health and the environment. This review serves as a reference for the research and development of acylglycerols using biocatalysts and reactors. It could be an interest to the food and pharmaceutical industries or individuals who are interested to explore this field. Several limitations associated with the overall research on production of acylglycerols are presented in the conclusion section.

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使用反应器脂肪酶催化合成酰基甘油的十年发展：系统评价

甘油酯化可产生多种有价值的化学品，近年来已成为人们极大兴趣的课题。脂肪酶催化的酰基甘油合成反应具有许多潜在的应用，包括在结构脂质、生物燃料和药物的生产中。与传统化学方法相比，它具有多种优点，包括更高的选择性、更温和的反应条件和更高的可持续性。在这篇系统综述中，我们总结了 2012 年至 2022 年发表的 52 篇关于脂肪酶催化合成酰基甘油的初步研究。深入讨论了使用各种脂肪酶合成酰基甘油时采用的不同类型的反应。使用脂肪酶作为生物催化剂合成酰基甘油是安全且可持续的，因为它可以减少对人类健康和环境造成危害的有毒有害有机溶剂和化学品的使用。该综述可为利用生物催化剂和反应器进行酰基甘油的研究和开发提供参考。这可能会引起食品和制药行业或有兴趣探索该领域的个人的兴趣。结论部分提出了与酰基甘油生产的整体研究相关的一些局限性。