In this research project, we first synthesized the magnetic manganese nanocatalyst by immobilizing the MnCl₂ on the surface of magnetic Fe₃O₄ nanoparticles modified with catechol and piperazine/phenanthroline ligand [Fe₃O₄@Catechol/PZ-Phen-MnCl₂], then we evaluated its catalytic performance in the synthesis of propargyl amines through the A³ and KA²-coupling three-component reactions aromatic aldehydes or ketones, with alkynes, and amines. FT-IR, SEM, TEM, EDX, XRD, TGA, VSM, ICP-OES and elemental mapping analyzes confirmed the successful synthesis of Fe₃O₄@Catechol/PZ-Phen-MnCl₂ nanocatalyst. The results of the coupling reactions confirmed that the Fe₃O₄@Catechol/PZ-Phen-MnCl₂ nanocomposite is a very efficient catalyst for the preparation of various derivatives of propargyl amines. This method has significant features compared to the previous methods, which can be mentioned as follows: synthesis of products with very high efficiency, carrying out the reaction under mild conditions and compatible with the environment, using green and recyclable catalyst, can being applicable to a wide range of substrates and providing NMR analysis for all propargyl amine products.

Graphical Abstract

中文翻译：

---

一种有吸引力且有效的制备炔丙胺的方法：提出一种用于形成 CN 键的新型磁性可重复使用的锰纳米催化剂

在本研究项目中，我们首先通过将MnCl ₂固定在儿茶酚和哌嗪/菲咯啉配体修饰的磁性Fe ₃ O ₄纳米颗粒表面合成了磁性锰纳米催化剂[Fe ₃ O ₄ @Catechol/PZ-Phen-MnCl ₂ ] ，然后我们通过芳香醛或酮、炔烃和胺的A ³和KA ²偶联三组分反应评价其在合成炔丙胺中的催化性能。 FT-IR、SEM、TEM、EDX、XRD、TGA、VSM、ICP-OES和元素图谱分析证实Fe ₃ O ₄ @Catechol/PZ-Phen-MnCl ₂纳米催化剂的成功合成。偶联反应结果证实Fe ₃ O ₄ @儿茶酚/PZ-Phen-MnCl ₂纳米复合材料是制备各种炔丙胺衍生物的非常有效的催化剂。该方法与以往的方法相比具有显着的特点，产品合成效率非常高，反应条件温和且与环境相容，使用的催化剂绿色可回收，可应用于工业领域。多种底物，并为所有炔丙胺产品提供 NMR 分析。

图形概要