New classes of thia/oxa-azaspiro[3.4]octanes are synthesized through the implementation of robust and step-economic routes. The targeted spirocycles have been designed to act as novel, multifunctional, and structurally diverse modules for drug discovery. Furthermore, enantioselective approaches to the spirocycles are reported.

中文翻译：

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用于药物发现的多功能模块的构建：新型Thia / Oxa-Azaspiro [3.4]辛烷的合成

通过实施稳健的分步经济路线，合成了新的硫杂/氧杂氮杂[3.4]辛烷类。目标螺环已被设计为可用于药物发现的新颖，多功能和结构多样的模块。此外，报道了螺环的对映选择性方法。