Huck, O, Mulhall, H, Rubin, G, et al. Akkermansia muciniphila reduces Porphyromonas gingivalis-induced inflammation and periodontal bone destruction. J Clin Periodontol. 2020; 47: 202–212. https://doi.org/10.1111/jcpe.13214

Concerns were raised by a third party regarding the appearance of Figure 2, suggesting that the A and D subpanels show identical images for the “H&E Control” and overlapping field of view for the “TRAP Pg”. The authors admitted to the image compilation error and were able to provide the original images. The authors confirm that all the experimental results and corresponding conclusions mentioned in the paper remain unaffected and sincerely apologize for this mistake. The corrected Figure 2 is shown as follows.

Erroneous Figure 2:

Corrected Figure 2:

It has also been noted, that the image subpanel displayed as “Lean – PBS” in Figure 1 a was previously published by the authors elsewhere. The authors confirmed that these are indeed identical images depicting the same PBS control group, used in both studies, yet the first published image was not correctly referenced. The authors apologize for the oversight. Please find the corrected caption of Figure 1 below:

Figure 1. A. muciniphila reduced calvarial tissue destruction induced by P. gingivalis injection. (a) Macroscopic view of the tissue destruction at calvarial site 3 days following injections of PBS (control), P. gingivalis alone (Pg), A. muciniphila alone (Akk), combined P. gingivalis and A. muciniphila (Pg + Akk) in lean and obese mice. The top left “Lean – PBS” subpanel was reproduced under the terms of the Creative Commons CC BY License. [Huck et al., 2019] Copyright © 2019, The Authors (b) Quantitative evaluation of the size of the lesions in the lean mice over time. (c) Quantitative evaluation of the size of the lesion in the obese mice over time. Results were analysed by ANOVA with differences considered significant at * p ≤ .05 between groups (n = 5/group). Pg: P. gingivalis-injected group; Akk: A. muciniphila-injected group; Pg + Akk: P. gingivalis + A. muciniphila-injected concomitantly.

哈克，O ，穆霍尔，H ，鲁宾，G ，等人。 Akkermansia muciniphila可减少牙龈卟啉单胞菌引起的炎症和牙周骨破坏。 J 临床牙周病杂志。 2020 年； 47 ： 202-212 。 https://doi.org/10.1111/jcpe.13214

第三方对图 2 的外观提出了担忧，表明 A 和 D 子面板显示“H&E Con​​trol”的相同图像以及“TRAP Pg”的重叠视野。作者承认图像编译错误并能够提供原始图像。作者确认论文中提到的所有实验结果和相应结论不受影响，并对这一错误表示诚挚的歉意。修正后的图2如下所示。

 错误图2：

 更正图 2：

还值得注意的是，图 1a 中显示为“Lean – PBS”的图像子面板是作者之前在其他地方发布的。作者证实，这些确实是两项研究中使用的描绘相同 PBS 对照组的相同图像，但第一个发布的图像未正确引用。作者为疏忽表示歉意。请在下面找到图 1 的更正标题：

图 1. A. muciniphila减少了牙龈卟啉单胞菌注射引起的颅骨组织破坏。 (a) 注射 PBS（对照）、单独牙龈卟啉单胞菌(Pg)、单独A. muciniphila (Akk)、组合牙龈卟啉单胞菌和A. muciniphila (Pg + Akk) 后 3 天颅骨部位组织破坏的宏观视图）在瘦小鼠和肥胖小鼠中。左上角的“精益 – PBS”子面板是根据 Creative Commons CC BY 许可证的条款复制的。 [Huck et al., 2019] 版权所有 © 2019，作者 (b) 随着时间的推移对瘦小鼠病变大小的定量评估。 (c) 随着时间的推移对肥胖小鼠病变大小的定量评估。结果通过方差分析进行分析，组间差异显着，* p ≤ .05（n = 5/组）。 Pg：牙龈卟啉单胞菌注射组； Akk： A. muciniphila注射组； Pg + Akk：同时注射P. gingivalis + A. muciniphila 。