BackgroundTo compare acceptance and preference of topical lidocaine gel anesthesia with articaine injection anesthesia in patients with moderate periodontitis undergoing scaling and root debridement.MethodsNinety‐one patients completed this randomized multicenter split‐mouth controlled study and underwent two separate periodontal treatment sessions on different days, one with a topical intrapocket lidocaine gel application and the other with an articaine injection anesthesia in a different order depending on randomization. Parameters measured were the patients’ preference for topical lidocaine gel anesthesia or injection anesthesia with articaine (primary efficacy criterion), their maximum and average pain, and their intensity of numbness as well as experience of side effects; the probing depth; and the dentists’ preference and their evaluations of handling/application, onset and duration of anesthetic effect, and patient compliance.ResultsAfter having experienced both alternatives, 58.3% of the patients preferred the topical lidocaine gel instillation into the periodontal pockets. The safety profile of the lidocaine gel differed positively from the safety profile of articaine injection in type and frequency of adverse drug reactions. The dentistsʼ acceptance and preference regarding either anesthetic method studied were balanced.ConclusionsInstillation of lidocaine gel into the periodontal pocket is a preferred alternative to injection anesthesia for most of the patients and an equivalent alternative for dentists in nonsurgical periodontal therapy.

中文翻译：

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非手术牙周治疗后局部利多卡因应用与阿替卡因注射麻醉的接受度和偏好评估：一项随机临床试验


背景旨在比较接受洁牙和牙根清创术的中度牙周炎患者对局部利多卡因凝胶麻醉与阿替卡因注射麻醉的接受度和偏好。 方法 91 名患者完成了这项随机多中心分口对照研究，并在不同日期接受了两次单独的牙周治疗疗程，一次是一种是局部使用袋内利多卡因凝胶，另一种是使用阿替卡因注射麻醉，具体顺序取决于随机化。测量的参数是患者对局部利多卡因凝胶麻醉或阿替卡因注射麻醉的偏好（主要疗效标准）、最大和平均疼痛、麻木程度以及副作用的经历；探测深度；以及牙医的偏好及其对操作/应用、麻醉效果的起效和持续时间以及患者依从性的评估。结果在经历了两种选择后，58.3%的患者更喜欢局部利多卡因凝胶滴注到牙周袋中。利多卡因凝胶的安全性与阿替卡因注射液的安全性在药物不良反应的类型和频率方面存在显着差异。牙医对所研究的两种麻醉方法的接受度和偏好是平衡的。结论对于大多数患者来说，将利多卡因凝胶滴入牙周袋是注射麻醉的首选替代方案，也是牙医非手术牙周治疗的等效替代方案。