Fibromuscular dysplasia is the most common cause of renovascular hypertension in young adults under 40 years old. It is potentially amenable to renal artery angioplasty, which frequently normalizes blood pressure. However, limited options exist if angioplasty is not technically possible, or restenosis occurs. Here, we describe 2 patients who presented with hypertension secondary to renal artery stenosis. In the first case, a young adult with hypertension secondary to renal artery stenosis (fibromuscular dysplasia), developed restenosis 11 weeks after an initially successful renal artery angioplasty. In the second case, a patient with neurofibromatosis type 1 was diagnosed with hypertension secondary to renal artery stenosis. Angioplasty was not possible due to multiple branch occlusions. Both individuals went on to have successful renal autotransplantations, which ultimately cured their hypertension. In this article, we review the background, indications, and blood pressure outcomes in relation to renal autotransplantation in nonatherosclerotic renal artery stenosis.

中文翻译：

---

自体肾移植治疗非动脉粥样硬化性肾动脉狭窄失控性高血压——2例报告及文献综述


纤维肌发育不良是 40 岁以下年轻人肾血管性高血压的最常见原因。它可能适合肾动脉血管成形术，这通常可以使血压正常化。然而，如果血管成形术在技术上不可行或发生再狭窄，则选择有限。在这里，我们描述了 2 名因肾动脉狭窄继发高血压的患者。在第一个病例中，一名患有继发于肾动脉狭窄（纤维肌性发育不良）的高血压的年轻成人在最初成功的肾动脉血管成形术后 11 周出现再狭窄。在第二个病例中，一名 1 型神经纤维瘤病患者被诊断为继发于肾动脉狭窄的高血压。由于多个分支闭塞，无法进行血管成形术。两人都成功进行了自体肾移植，最终治愈了他们的高血压。在本文中，我们回顾了非动脉粥样硬化性肾动脉狭窄患者自体肾移植的背景、适应症和血压结果。