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Palmitoleic Acid Ameliorates Metabolic Disorders and Inflammation by Modulating Gut Microbiota and Serum Metabolites
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-03-21 , DOI: 10.1002/mnfr.202300749
Junhui Zhang 1, 2 , Minjie Zhao 2 , Huilin Yu 2 , Qianqian Wang 2 , Fei Shen 2 , Haiying Cai 3 , Fengqin Feng 2 , Jun Tang 1, 2, 4
Affiliation  

Palmitoleic acid (POA) is an omega-7 monounsaturated fatty acid that has been suggested to improve metabolic disorders. However, it remains unclear whether gut microbiota plays a role in the amelioration of metabolic disorders by POA. This study aims to investigate the regulation of POA on metabolism, as well as systemic inflammation in HFD-fed mice from the perspective of serum metabolome and gut microbiome.

中文翻译:

棕榈油酸通过调节肠道微生物群和血清代谢物来改善代谢紊乱和炎症

棕榈油酸 (POA) 是一种 omega-7 单不饱和脂肪酸,被认为可以改善代谢紊乱。然而,肠道微生物群是否在 POA 改善代谢紊乱中发挥作用仍不清楚。本研究旨在从血清代谢组和肠道微生物组的角度探讨POA对高脂饮食小鼠代谢及全身炎症的调节作用。
更新日期:2024-03-21
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