当前位置：
X-MOL 学术
›
Angew. Chem. Int. Ed.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
2-Oxabicyclo[2.1.1]hexanes: Synthesis, Properties, and Validation as Bioisosteres of ortho- and meta-Benzenes
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2024-03-11 , DOI: 10.1002/anie.202319831 Vadym V. Levterov 1 , Yaroslav Panasiuk 1 , Oleg Shablykin 1 , Oleksandr Stashkevych 1 , Kateryna Sahun 1 , Artur Rassokhin 1 , Iryna Sadkova 1 , Dmytro Lesyk 2 , Anna Anisiforova 2 , Yuliia Holota 2 , Petro Borysko 2 , Iryna Bodenchuk 2 , Nataliya M. Voloshchuk 3 , Pavel K. Mykhailiuk 4
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2024-03-11 , DOI: 10.1002/anie.202319831 Vadym V. Levterov 1 , Yaroslav Panasiuk 1 , Oleg Shablykin 1 , Oleksandr Stashkevych 1 , Kateryna Sahun 1 , Artur Rassokhin 1 , Iryna Sadkova 1 , Dmytro Lesyk 2 , Anna Anisiforova 2 , Yuliia Holota 2 , Petro Borysko 2 , Iryna Bodenchuk 2 , Nataliya M. Voloshchuk 3 , Pavel K. Mykhailiuk 4
Affiliation
|
A general and practical approach towards substituted 2-oxabicyclo[2.1.1]hexanes has been developed. The obtained compounds have been incorporated into the structure of five drugs and three agrochemicals, and have been validated biologically as bioisosteres of ortho- and meta-benzenes.
中文翻译：
2-氧杂双环[2.1.1]己烷：合成、性质以及作为邻苯和间苯生物等排体的验证
已经开发出一种通用且实用的取代 2-氧杂双环[2.1.1]己烷的方法。所获得的化合物已被纳入五种药物和三种农用化学品的结构中，并已作为邻苯和间苯的生物等排体进行了生物学验证。
更新日期：2024-03-11
中文翻译：
2-氧杂双环[2.1.1]己烷：合成、性质以及作为邻苯和间苯生物等排体的验证
已经开发出一种通用且实用的取代 2-氧杂双环[2.1.1]己烷的方法。所获得的化合物已被纳入五种药物和三种农用化学品的结构中，并已作为邻苯和间苯的生物等排体进行了生物学验证。
京公网安备 11010802027423号