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All fibroblasts are equal, but some are more equal than others
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2024-03-11 , DOI: 10.1038/s41584-024-01097-6
Chrissy Bolton , Adam P. Croft

Characteristic patterns of joint involvement exist in different forms of arthritis. Research now indicates that epigenetic programming of synovial fibroblasts diversifies their response to inflammatory cascades, leading to this anatomical variation in arthritis and its response to treatment.

中文翻译:

所有成纤维细胞都是平等的,但有些成纤维细胞比其他成纤维细胞更平等

不同形式的关节炎存在关节受累的特征模式。现在的研究表明,滑膜成纤维细胞的表观遗传编程使其对炎症级联反应的反应多样化,从而导致关节炎的这种解剖学变异及其对治疗的反应。
更新日期:2024-03-11
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