Oxazoles are an important class of biologically active compounds in the pharmaceutical chemistry and are considered as the main structure of many biologically active compounds. Therefore, the development of efficient and ecofriendly catalytic systems for the preparation of thiazole derivatives is a key research topic in organic synthesis. During the last decade, chemistry science especially organic synthesis witnessed a huge revolution in the field of using magnetic nanocomposites as the catalyst. Magnetic nanoparticles not only have high stability, but also their surface can be easily modified and an efficient catalyst can be prepared from this method. In addition, the most important feature of magnetic nanocatalysts is their simple separation from the reaction mixture using only an external magnet. In these years, a series of magnetic nanocatalysts were reported for the synthesis of various derivatives of oxazoles, and in this article, we are going to review these methods and mention the characteristics of these catalytic systems. Based on our complete search in the literature, this is the first review-article on the application of magnetic nanocatalysts in the synthesis of oxazole derivatives. In our opinion, this review is a good source for synthetic chemists who work in the field of synthesis of oxazole derivatives and whose research is focused on magnetic nanocatalysts.

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恶唑合成综述：磁可恢复催化剂的研究

恶唑是药物化学中一类重要的生物活性化合物，被认为是许多生物活性化合物的主要结构。因此，开发高效、环境友好的催化体系来制备噻唑衍生物是有机合成领域的一个重点研究课题。在过去的十年中，化学科学特别是有机合成见证了使用磁性纳米复合材料作为催化剂领域的巨大革命。磁性纳米颗粒不仅具有较高的稳定性，而且其表面易于修饰，通过该方法可以制备出高效的催化剂。此外，磁性纳米催化剂最重要的特征是仅使用外部磁铁即可从反应混合物中简单分离。近年来，报道了一系列磁性纳米催化剂用于合成各种恶唑衍生物，在本文中，我们将回顾这些方法并提及这些催化体系的特点。基于我们对文献的全面检索，这是第一篇关于磁性纳米催化剂在恶唑衍生物合成中应用的综述文章。我们认为，这篇综述对于从事恶唑衍生物合成领域工作且研究重点是磁性纳米催化剂的合成化学家来说是一个很好的参考资料。

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