A newly developed UPLC-MS/MS method for simultaneous quantitative analysis of ajuforrestin A, ajuforrestin B, ajugamacrin and 8-O-acetylharpagide derived from Ajuga plants in mice blood and the in vivo pharmacokinetics,Drug Development and Industrial Pharmacy

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A newly developed UPLC-MS/MS method for simultaneous quantitative analysis of ajuforrestin A, ajuforrestin B, ajugamacrin and 8-O-acetylharpagide derived from Ajuga plants in mice blood and the in vivo pharmacokinetics
Drug Development and Industrial Pharmacy ( IF 2.4 ) Pub Date : 2024-03-14 , DOI: 10.1080/03639045.2024.2328731
Xiuwei Shen ₁ , Chen Chen ₂ , Congcong Wen ₃ , Shuaishuai Yu ₄ , Huamin Liu ₃ , Xiaomin Gao ₅ , Lianguo Chen ₂

Affiliation

To develop a sensitive and fast detection method via ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to assess the concentration of ajuforrestin A, ajuforrestin B, aju...

中文翻译：

新开发的 UPLC-MS/MS 方法可同时定量分析小鼠血液中 Ajuforrestin A、ajuforrestin B、ajugamacrin 和 8-O-乙酰哈巴苷及其体内药代动力学

通过超高效液相色谱-串联质谱 (UPLC-MS/MS) 开发一种灵敏、快速的检测方法，以评估 ajuforrestin A、ajuforrestin B、aju...

更新日期：2024-03-14

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