Adaptive Encapsulation of ω-Amino Acids and Their Guanidinium–Amide Congeners,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Adaptive Encapsulation of ω-Amino Acids and Their Guanidinium–Amide Congeners
Organic Letters ( IF 4.9 ) Pub Date : 2016-10-19 00:00:00 , DOI: 10.1021/acs.orglett.6b02802
Wei-Xu Feng _{1,

2} , Arie van der Lee ₂ , Yves-Marie Legrand ₂ , Eddy Petit ₂ , Dan Dumitrescu ₂ , Cheng-Yong Su ₁ , Mihail Barboiu _{1,

2}

Affiliation

The binding and the encapsulation of the 6-aminohexanoic acid (1) and 11-aminoundecanoic acid (2) are achieved in aqueous solution and in crystalline Pyrene-box cages. Unexpectedly, the amino-guanidinium AG⁺ and the amino acids 1 or 2 are reacting in aqueous solution in the absence and in the presence of Pyrene-box cages. The formation of an amide bond between a carboxylic acid and the amino-guanidine unit under mild acidic conditions in water without the use a coupling reagent is extremely interesting and unexpected. The resulted adducts AG1 and AG2 show adaptive binding behaviors and compressions.

中文翻译：

ω-氨基酸及其胍基-酰胺同系物的自适应包封

6-氨基己酸（1）和11-氨基十一酸（2）的结合和封装是在水溶液和结晶的盒笼中实现的。出乎意料的是，在不存在和存在P盒笼的情况下，氨基胍AG ⁺和氨基酸1或2在水溶液中反应。不使用偶联剂在水中在弱酸性条件下在羧酸和氨基胍单元之间形成酰胺键是非常令人感兴趣和出乎意料的。所得的加合物AG1和AG2显示出自适应的结合行为和压缩。

更新日期：2016-10-19

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南