Trojan horse inhibitor of protein neddylation: The ubiquitin‐like protein Nedd8 goes through an enzymatic cascade to modify key cellular proteins, such as cullin‐RING ubiquitin ligase (CRL). Phage selection identified short peptides that function as a Trojan horse to covalently react with NAE and thus block Nedd8 transfer through the cascade.

中文翻译：

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噬菌体展示识别作为 Nedd8 转移级联抑制剂的 Nedd8 模拟肽

蛋白质neddylation的特洛伊木马抑制剂：泛素样蛋白Nedd8通过酶促级联来修饰关键细胞蛋白质，例如cullin-RING泛素连接酶（CRL）。噬菌体选择鉴定了短肽，其作为特洛伊木马与 NAE 共价反应，从而阻止 Nedd8 通过级联转移。