Structural variants (SVs) are currently analyzed using a combination of conventional methods; however, this approach has limitations. Optical genome mapping (OGM), an emerging technology for detecting SVs using a single-molecule strategy, has the potential to replace conventional methods. We compared OGM with conventional diagnostic methods for detecting SVs in various hematologic malignancies.

中文翻译：

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光学基因组作图与血液恶性肿瘤结构变异检测的传统诊断方法的比较。


目前，结构变体 (SV) 的分析采用传统方法的组合；然而，这种方法有局限性。光学基因组图谱 (OGM) 是一种利用单分子策略检测 SV 的新兴技术，有可能取代传统方法。我们将 OGM 与检测各种血液恶性肿瘤中 SV 的传统诊断方法进行了比较。