A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy,Chemical Communications

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A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy
Chemical Communications ( IF 4.3 ) Pub Date : 2024-03-01 , DOI: 10.1039/d3cc06205h
Ying Chen _{1,

2,

3} , Jing Zhai _{1,

2,

3} , Shiqi Wei _{1,

2,

3} , Aidong Tang _{1,

2,

3} , Huaming Yang _{1,

2,

3}

Affiliation

A Fe(III) intercalated montmorillonite nanoplatform (Fe-MMT) was engineered for doxorubicin (DOX) loading. The constructed Fe-MMT/DOX nanoplatform could not only improve the production of H₂O₂ to enhance chemodynamic therapy but interfere with DNA damage repair to amplify the efficacy of DOX, proving an ideal combination of chemotherapy and chemodynamic therapy.

中文翻译：

用于化学/化学动力学联合治疗的 Fe(III) 插层粘土纳米平台

Fe( III )插层蒙脱石纳米平台(Fe-MMT)被设计用于负载阿霉素(DOX)。构建的Fe-MMT/DOX纳米平台不仅可以提高H ₂ O ₂的产生以增强化学动力学治疗，而且可以干扰DNA损伤修复以放大DOX的疗效，证明了化疗和化学动力学治疗的理想组合。

更新日期：2024-03-01

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