1,5-Pentanediol as an important chemical intermediate is commonly used for the manufacture of polyesters and polyurethanes. A novel process was developed for the production of bio-based 1,5-pentanediol (1,5-PDO) from 3,4-dihydro-2-pyran (DHP) and acetic acid (AA) in this work. The esterification of DHP and AA achieved a 59.8% DHP conversion and 91.2% tetrahydropyran-2-yl acetate selectivity (THPOAc) at 373 ​K for 1 ​h and DHP/AA molar ratio of 1 without catalyst. Then the 1,5-PDO with selectivity of 54.5% was obtained from THPOAc hydrogenation over Cu/Zn/Al catalyst under the conditions of 453 ​K and 50 ​bar. The higher dispersion of Cu nanoparticles, the larger surface area of metallic Cu, the higher amount of Cu active sites and the lower acidity of Cu/Zn/Al catalyst were beneficial for the hydrogenation of THPOAc to 1,5-PDO.

中文翻译：

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由3,4-二氢-2H-吡喃和乙酸通过连续酯化和加氢反应生产1,5-戊二醇

1,5-戊二醇作为重要的化学中间体，通常用于制造聚酯和聚氨酯。这项工作开发了一种从 3,4-二氢-2-吡喃 (DHP) 和乙酸 (AA) 生产生物基 1,5-戊二醇 (1,5-PDO) 的新工艺。 DHP 和 AA 的酯化反应在 373 K 下进行 1 h，DHP/AA 摩尔比为 1，无需催化剂，DHP 转化率为 59.8%，四氢吡喃-2-乙酸酯选择性 (THPOAc) 为 91.2%。然后在 453 K 和 50 bar 的条件下，在 Cu/Zn/Al 催化剂上进行 THPOAc 加氢，得到选择性为 54.5% 的 1,5-PDO。 Cu纳米颗粒较高的分散度、较大的金属Cu表面积、较多的Cu活性位点以及Cu/Zn/Al催化剂较低的酸性有利于THPOAc加氢生成1,5-PDO。