Erianin is an important bibenzyl compound in dendrobium and has a wide spectrum of pharmacological properties. Since Erianin was discovered, abundant results have been achieved in the in vitro synthesis, structural modification, and pharmacological mechanism research. Researchers have developed a series of simple and efficient in vitro synthesis methods to improve the shortcomings of poor water solubility by replacing the chemical structure or coating it in nanomaterials. Erianin has a broad anti-tumor spectrum and significant anti-tumor effects. In addition, Erianin also has pharmacological actions like immune regulation, anti-inflammatory, and anti-angiogenesis. A comprehensive understanding of the synthesis, metabolism, structural modification, and pharmacological action pathways of Erianin is of great value for the utilization of Erianin. Therefore, this review conducts a relatively systematic look back at Erianin from the above four aspects, to give a reference for the evolvement and further appliance of Erianin.

中文翻译：

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毛兰素药理机制、体内代谢及结构修饰研究进展


毛兰素是石斛中重要的联苄基化合物，具有广泛的药理特性。自发现毛兰素以来，在体外合成、结构修饰和药理机制研究方面取得了丰富的成果。研究人员开发了一系列简单高效的体外合成方法，通过替换化学结构或用纳米材料包覆其来改善水溶性差的缺点。毛兰素抗肿瘤谱广，抗肿瘤作用显着。此外，毛兰素还具有免疫调节、抗炎、抗血管生成等药理作用。全面了解毛兰素的合成、代谢、结构修饰和药理作用途径，对于毛兰素的利用具有重要价值。因此，本文从上述四个方面对毛兰素进行了较为系统的回顾，以期为毛兰素的演变和进一步应用提供参考。