The efficient synthesis of a range of biologically significant functionalized 3-aminopyrrolidine-2,5-dione derivatives was achieved from -fused imidazole derivatives (GBB(Groebke-Blackburn-Bienaymé) reaction products) through structural rearrangement by the treatment of aliphatic acid silver salt. The reaction features wide substrates scope, exceptionally mild conditions, moderate-to-good yields and good diastereoselectivities.

中文翻译：

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通过脂肪酸银介导的GBB氧化后修饰反应合成功能化3-氨基-吡咯烷-2,5-二酮

以稠合咪唑衍生物（GBB（Groebke-Blackburn-Bienaymé）反应产物）为原料，通过脂肪酸银盐处理进行结构重排，高效合成了一系列具有生物学意义的功能化3-氨基吡咯烷-2,5-二酮衍生物。该反应具有底物范围广、条件极其温和、产率中等至良好以及良好的非对映选择性的特点。