The Jr^a antigen is a high-prevalence red blood cell (RBC) antigen. Reports on cases of fatal hemolytic disease of the fetus and newborn and acute hemolytic transfusion reactions suggest that antibodies against Jr^a (anti-Jr^a) have potential clinical significance. Identifying anti-Jr^a is challenging owing to a lack of commercially available antisera. We developed an alternative approach to rapidly predict the presence of anti-Jr^a using the TaqMan single-nucleotide polymorphism (SNP)-genotyping method.

中文翻译：

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评估用于快速预测抗 Jra 抗体存在的 TaqMan Jra 基因分型方法。


Jr ^a抗原是一种高流行率的红细胞 (RBC) 抗原。胎儿和新生儿致命性溶血病以及急性溶血性输血反应病例的报道表明，抗Jr ^a抗体（抗Jr ^a ）具有潜在的临床意义。由于缺乏市售抗血清，识别抗 Jr ^a具有挑战性。我们开发了一种替代方法，使用 TaqMan 单核苷酸多态性 (SNP) 基因分型方法快速预测抗 Jr ^a的存在。