A one-pot, sequential three-component reaction between salicylaldehyde, indole, and 2-bromoprop-2-ene-1-sulfonyl fluoride (BPESF) has been demonstrated for the synthesis of sulfonyl fluoride substituted 4H-chromene derivatives in moderate to excellent yields (45%–94%). This one-pot sequential method features easily available starting materials, wide substrate scope, mild conditions, and great efficiency.

中文翻译：

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一锅法三组分合成吲哚基-4H-色烯-3-磺酰氟：一类重要药效团

水杨醛、吲哚和 2-溴丙-2-烯-1-磺酰氟 (BPESF) 之间的一锅连续三组分反应已被证明可合成磺酰氟取代的 4 H-色烯衍生物，合成效率中等至优异产率（45%–94%）。该一锅序贯法具有起始原料易得、底物范围广、条件温和、效率高等特点。