Convergence of Nanotechnology and Bacteriotherapy for Biomedical Applications,Advanced Science

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Convergence of Nanotechnology and Bacteriotherapy for Biomedical Applications
Advanced Science ( IF 14.3 ) Pub Date : 2024-02-15 , DOI: 10.1002/advs.202309295
Jun Liu _{1,

2,

3} , Sichen Yuan _{1,

2,

3} , Alexa Bremmer ₁ , Quanyin Hu _{1,

2,

3}

Affiliation

Bacteria have distinctive properties that make them ideal for biomedical applications. They can self-propel, sense their surroundings, and be externally detected. Using bacteria as medical therapeutic agents or delivery platforms opens new possibilities for advanced diagnosis and therapies. Nano-drug delivery platforms have numerous advantages over traditional ones, such as high loading capacity, controlled drug release, and adaptable functionalities. Combining bacteria and nanotechnologies to create therapeutic agents or delivery platforms has gained increasing attention in recent years and shows promise for improved diagnosis and treatment of diseases. In this review, design principles of integrating nanoparticles with bacteria, bacteria-derived nano-sized vesicles, and their applications and future in advanced diagnosis and therapeutics are summarized.

中文翻译：

纳米技术与细菌疗法在生物医学应用中的融合

细菌具有独特的特性，使其成为生物医学应用的理想选择。它们可以自我推进、感知周围环境并被外部检测到。使用细菌作为医学治疗剂或递送平台为先进的诊断和治疗开辟了新的可能性。纳米药物递送平台比传统药物递送平台具有许多优势，例如高负载能力、受控药物释放和适应性强的功能。近年来，将细菌和纳米技术结合起来创造治疗剂或递送平台越来越受到关注，并显示出改善疾病诊断和治疗的希望。在这篇综述中，总结了纳米颗粒与细菌、细菌衍生的纳米囊泡整合的设计原理，及其在高级诊断和治疗中的应用和未来。

更新日期：2024-02-15

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