Background: Physical skeletal loading can affect the bone mineral density (BMD). This study investigated the association between BMD and dynamic foot pressure during gait. Methods: A total of 104 patients (mean age, 62.6 ± 12.4 years; 23 male and 81 female) who underwent dual x-ray absorptiometry and pedobarography were included. BMD values of the lumbar spine, femoral neck, and total femur were assessed. The mean and maximum pressures were measured at the hallux, lesser toes, 1st metatarsal head, 2nd and 3rd metatarsal heads, 4th and 5th metatarsal heads, midfoot, medial heel, and lateral heel. Multivariable regression analysis was performed to identify factors significantly associated with BMD. Results: The lumbar spine BMD was significantly associated with the mean pressure at the 4th and 5th metatarsal heads (p = 0.041, adjusted R2 of model = 0.081). The femoral neck BMD was significantly associated with the maximum pressure at the 2nd and 3rd metatarsal heads (p = 0.002, adjusted R2 = 0.213). The total femoral BMD also showed a significant association with the maximum pressure at the 2nd and 3rd metatarsal heads (p = 0.003, adjusted R2 = 0.360). Conclusions: Foot plantar pressure during gait was significantly associated with BMD, and could potentially be used to predict the presence of osteoporosis. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

中文翻译：

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步行时动态足部压力

背景：物理骨骼负荷会影响骨矿物质密度 (BMD)。本研究调查了步态中 BMD 与动态足部压力之间的关联。 方法：共有 104 名患者（平均年龄 62.6 ± 12.4 岁；23 名男性和 81 名女性）接受了双 X 射线骨密度测定和足底压力描记术。评估腰椎、股骨颈和总股骨的 BMD 值。在拇趾、小脚趾、第一跖骨头、第二和第三跖骨头、第四和第五跖骨头、中足、内侧脚跟和外侧脚跟处测量平均和最大压力。进行多变量回归分析以确定与 BMD 显着相关的因素。 结果：腰椎 BMD 与第 4 和第 5 跖骨头的平均压力显着相关（p = 0.041，调整 R2模型 = 0.081)。股骨颈 BMD 与第二和第三跖骨头的最大压力显着相关（p = 0.002，调整 R2= 0.213）。总股骨 BMD 还显示与第二和第三跖骨头的最大压力显着相关（p = 0.003，调整后的 R2= 0.360）。 结论：步态期间的足底压力与 BMD 显着相关，并且有可能用于预测骨质疏松症的存在。 证据级别：预后三级。有关证据级别的完整描述，请参阅作者须知。