Both the gut and the tumour microbiome are now established as crucial regulators of cancer phenotypes and have been implicated in cancer initiation, progression and therapy response. Although the role of bacteria in these processes is beginning to be unravelled, the relevance of fungi is only just emerging. In this Viewpoint, we asked experts to discuss the current knowledge on the mycobiome–cancer connection and share their opinion on how to best solve open questions. In this Viewpoint article, we asked three scientists working on the cancer mycobiome to provide their opinions on advancements and challenges and what the future holds for this exciting field of cancer research.

中文翻译：

---

 癌症中的真菌


肠道和肿瘤微生物组现已被确定为癌症表型的关键调节因子，并且与癌症的发生、进展和治疗反应有关。尽管细菌在这些过程中的作用已经开始被阐明，但真菌的相关性才刚刚出现。在这个观点中，我们请专家讨论了真菌生物组与癌症之间联系的最新知识，并就如何最好地解决悬而未决的问题分享了他们的意见。在这篇观点文章中，我们请三位研究癌症真菌组的科学家就这一令人兴奋的癌症研究领域的进展和挑战以及未来的前景提供意见。