Effective wound management is important, as millions of people suffer traumatic injuries and surgical operations annually. Proper wound closure is essential for the structural and functional restoration of damaged tissues. In addition to conventional sutures, various advanced surgical materials with multiple functions have been developed for more reliable and improved wound healing performance in the past few years. Here, polymeric surgical materials for soft tissue wound closure are comprehensively reviewed, including both commercially available materials and newly developed materials. These materials, based on natural, synthetic or composite polymers, are classified and discussed as invasive and non-invasive surgical materials. Their properties (antibacterial, hemostatic, stimuli-responsive, drug delivery, or a combination thereof) are critically analysed in the context of improving wound healing. Moreover, how to tune these properties (e.g., chemical grafting of antibacterial moieties, nano-enabled regulation of hemostasis, dual stimuli-responsive design, etc.) are clearly discussed. Finally, challenges in the field and potential solutions to tackle them are also proposed. This review should inspire more research efforts to develop the next generation of promising surgical polymeric materials for clinical applications.

中文翻译：

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调整外科聚合材料的性能以改善软组织伤口的闭合和愈合

有效的伤口管理非常重要，因为每年有数百万人遭受外伤和外科手术。正确的伤口闭合对于受损组织的结构和功能恢复至关重要。除了传统的缝合线外，过去几年还开发了各种具有多种功能的先进手术材料，以提高伤口愈合性能并提高可靠性。在这里，对用于软组织伤口闭合的聚合物外科材料进行了全面的综述，包括市售材料和新开发的材料。这些基于天然、合成或复合聚合物的材料被分类和讨论为侵入性和非侵入性手术材料。在改善伤口愈合的背景下，对它们的特性（抗菌、止血、刺激响应、药物输送或其组合）进行了严格的分析。此外，还清楚地讨论了如何调整这些特性（例如，抗菌部分的化学接枝、纳米止血调节、双重刺激响应设计等）。最后，还提出了该领域的挑战和解决这些问题的潜在解决方案。这项综述应该会激发更多的研究工作，以开发用于临床应用的下一代有前景的外科聚合材料。