Phlorizin, as a flavonoid from a wide range of sources, is gradually becoming known for its biological activity. Phlorizin can exert antioxidant effects by regulating the IL-1β/IKB-α/NF-KB signaling pathway. At the same time, it exerts its antibacterial activity by reducing intracellular DNA agglutination, reducing intracellular protein and energy synthesis, and destroying intracellular metabolism. In addition, phlorizin also has various pharmacological effects such as antiviral, antidiabetic, antitumor, and hepatoprotective effects. Based on domestic and foreign research reports, this article reviews the plant sources, extraction, and biological activities of phlorizin, providing a reference for improving the clinical application of phlorizin.

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重要葡萄糖苷根皮苷的生物活性及机制研究进展

根皮苷作为一种来源广泛的黄酮类化合物，因其生物活性而逐渐为人所知。根皮苷可通过调节IL-1β/IKB-α/NF-KB信号通路发挥抗氧化作用。同时，它通过减少细胞内DNA凝集，减少细胞内蛋白质和能量合成，破坏细胞内代谢来发挥抗菌活性。此外，根皮苷还具有抗病毒、抗糖尿病、抗肿瘤、保肝等多种药理作用。本文结合国内外研究报道，对根皮苷的植物来源、提取方法及生物活性进行综述，为提高根皮苷的临床应用提供参考。