Peri-implantitis is a plaque-associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri-implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri-implantitis has become a major disease burden in dentistry. An understanding of the diagnosis, etiology and pathogenesis, epidemiology, and treatment of peri-implantitis must be a central component in undergraduate and postgraduate training programs in dentistry. In view of the strong role of European research in periodontology and implant dentistry, the focus of this review was to address peri-implantitis from a European perspective. One component of the work was to summarize new and reliable data on patients with dental implants to underpin the relevance of peri-implantitis from a population perspective. The nature of the peri-implantitis lesion was evaluated through results presented in preclinical models and evaluations of human biopsy material together with an appraisal of the microbiological characteristics. An overview of strategies and outcomes presented in clinical studies on nonsurgical and surgical treatment of peri-implantitis is discussed with a particular focus on end points of therapy and recommendations presented in the S3 level Clinical Practice Guideline for the prevention and treatment of peri-implant diseases.

中文翻译：

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种植体周围炎的病因、发病机制和治疗：欧洲视角


种植体周围炎是发生在牙种植体周围组织中的一种与牙菌斑相关的病理状况。其特征是种植体周围粘膜炎症和支撑骨逐渐丧失。在过去的 30 年里，种植体周围炎已成为牙科的主要疾病负担。了解种植体周围炎的诊断、病因和发病机制、流行病学和治疗必须是牙科本科和研究生培训计划的核心组成部分。鉴于欧洲研究在牙周病学和种植牙科方面的重要作用，本次综述的重点是从欧洲的角度解决种植体周围炎。这项工作的一个组成部分是总结有关种植牙患者的新的可靠数据，以从人群的角度支持种植体周围炎的相关性。通过临床前模型中呈现的结果和人体活检材料的评估以及微生物学特征的评估来评估种植体周围炎病变的性质。讨论了种植体周围炎的非手术和手术治疗临床研究中提出的策略和结果的概述，特别关注治疗终点和 S3 级种植体周围疾病预防和治疗临床实践指南中提出的建议。