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Genetics unravels protein–metabolite relationships
Trends in Endocrinology & Metabolism ( IF 11.4 ) Pub Date : 2024-01-31 , DOI: 10.1016/j.tem.2024.01.008
James R Hilser 1 , Aldons J Lusis 2 , Hooman Allayee 1
Affiliation  

Integrating molecular traits into genetic studies enhances our understanding of how DNA variation influences complex clinical and physiological phenotypes. In a recent article, apply this systems genetics approach with proteomics and metabolomics data in plasma from humans to identify and validate several previously unrecognized causal protein–metabolite associations.

中文翻译:


遗传学揭示蛋白质与代谢物的关系



将分子特征整合到遗传学研究中可以增强我们对 DNA 变异如何影响复杂的临床和生理表型的理解。在最近的一篇文章中,应用这种系统遗传学方法与人类血浆中的蛋白质组学和代谢组学数据来识别和验证一些以前未被识别的蛋白质-代谢物因果关系。
更新日期:2024-01-31
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