Abstract

The possibilities of the synthesis of new derivatives of quinazolin-4(3H)-ones by the reactions of different functionalized anthranilic acids with imino ether generated in situ from 2-cyanopyrimidine were studied. It was shown that the presence of different substituents in the anthranilic acids, including halogen atoms, methoxy and methyl groups, did not interfere with the reaction.

中文翻译：

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邻氨基苯甲酸与原位产生的嘧啶-2-碳酰亚胺甲酯环缩合合成 2-(嘧啶-2-基)喹唑啉-4(3H)-酮

摘要

研究了通过不同官能化的邻氨基苯甲酸与2-氰基嘧啶原位生成的亚氨基醚反应合成新的喹唑啉-4(3H)-酮衍生物的可能性。结果表明，邻氨基苯甲酸中不同取代基的存在，包括卤素原子、甲氧基和甲基，不会干扰反应。