Here we present the systematic analysis of conversion of 6-thioguanosine derivatives into unsymmetrical disulphides. Within the work we explored three known strategies for the preparation of disulphide bonds for 6-thioguanosine and its phosphorylated derivatives. We have shown that obtained derivatives are stable under certain conditions and can be easily further expanded using various tags depending on need.

中文翻译：

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探索将 6-硫鸟苷衍生物转化为不对称二硫化物的优化方法

在这里，我们对 6-硫鸟苷衍生物转化为不对称二硫化物进行了系统分析。在工作中，我们探索了三种已知的制备 6-硫鸟苷及其磷酸化衍生物二硫键的策略。我们已经证明，所获得的衍生物在某些条件下是稳定的，并且可以根据需要使用各种标签轻松地进一步扩展。