The spread of diseases caused by bacterial adhesion and immobilization in public places constitutes a serious threat to public health. Prevention of bacteria spread by the construction of an antibacterial surface takes precedence over post-infection treatment. Herein, we demonstrate an effective antibacterial surface with strong wear resistance by constructing cationic engineered nanodiamonds (C-NDs). The C-NDs with positive surface potentials interact effectively with bacteria through electrostatic interactions, where the C-NDs act on the phospholipid bilayer and lead to bacterial membrane collapse and rupture through hydrogen bonding and residual surface oxygen-containing reactive groups. In this case, bactericidal rate of 99.99% and bacterial biofilm inhibition rate of more than 80% can be achieved with the C-NDs concentration of 1 mg/mL. In addition, the C-NDs show outstanding antibacterial stability, retaining over 87% of the antibacterial effect after stimulation by adverse environments of heat, acid, and external abrasion. Therefore, an antibacterial surface with high wear resistance obtained by integrating C-NDs with commercial plastics has been demonstrated. The antibacterial surface with a mass fraction of 1 wt.% C-NDs improved abrasion resistance by 3981 times, with 99% killing of adherent bacteria. This work provides an effective strategy for highly efficient antibacterial wear-resistant surface, showing great practical applications in public health environments.

公共场所细菌粘附和固定引起的疾病传播对公众健康构成严重威胁。通过构建抗菌表面来预防细菌传播优先于感染后治疗。在此，我们通过构建阳离子工程纳米金刚石（C-ND）展示了具有强耐磨性的有效抗菌表面。具有正表面电位的C-ND通过静电相互作用与细菌有效地相互作用，其中C-ND作用于磷脂双层，并通过氢键和残留的表面含氧反应基团导致细菌膜塌陷和破裂。此时，C-NDs浓度为1 mg/mL时，杀菌率可达99.99%，细菌生物膜抑制率可达80%以上。此外，C-ND表现出优异的抗菌稳定性，在热、酸、外部磨损等不利环境刺激后仍能保持87%以上的抗菌效果。因此，通过将 C-ND 与商业塑料相结合获得的具有高耐磨性的抗菌表面已被证明。质量分数为1 wt.%的C-NDs抗菌表面的耐磨性提高了3981倍，对附着细菌的杀灭率达到99%。这项工作为高效抗菌耐磨表面提供了一种有效的策略，在公共卫生环境中展示了巨大的实际应用价值。