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Social victimization, default mode network connectivity, and psychotic-like experiences in adolescents
Schizophrenia Research ( IF 3.6 ) Pub Date : 2024-01-23 , DOI: 10.1016/j.schres.2024.01.019
Abhishek Saxena 1 , Shangzan Liu 2 , Elizabeth D Handley 1 , David Dodell-Feder 1
Affiliation  

Social victimization (SV) and altered neural connectivity have been associated with each other and psychotic-like experiences (PLE). However, research has not directly examined the associations between these variables, which may speak to mechanisms of psychosis-risk. Here, we utilized two-year follow-up data from the Adolescent Brain Cognitive Development study to test whether SV increases PLE through two neural networks mediating socio-affective processes: the default mode (DMN) and salience networks (SAN).

中文翻译:


青少年的社会受害、默认模式网络连接和类似精神病的经历



社会受害(SV)和神经连接改变相互关联,并且与精神病样经历(PLE)相关。然而,研究尚未直接检验这些变量之间的关联,这可能说明了精神病风险的机制。在这里,我们利用青少年大脑认知发展研究的两年跟踪数据来测试 SV 是否通过调节社会情感过程的两个神经网络:默认模式 (DMN) 和显着网络 (SAN) 来增加 PLE。
更新日期:2024-01-23
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