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Innovative Therapeutic Strategies in TYK2-Targeted Treatments: From Cancer to Autoimmune Disorders
ACS Medicinal Chemistry Letters ( IF 3.5 ) Pub Date : 2024-01-23 , DOI: 10.1021/acsmedchemlett.4c00004
Robert B. Kargbo 1
Affiliation  

Recent advancements in therapeutic approaches targeting tyrosine kinase 2 (TYK2) have shown promising results across various medical fields, including oncology and immunology. TYK2, a Janus kinase (JAK) family member, plays a significant role in cytokine signaling and immune regulation. This Patent Highlight explores the latest developments in TYK2 inhibitors, highlighting their potential in treating diverse conditions such as cancer, alopecia areata, and psoriatic arthritis.

中文翻译:

TYK2 靶向治疗的创新治疗策略:从癌症到自身免疫性疾病

针对酪氨酸激酶 2 (TYK2) 的治疗方法的最新进展在包括肿瘤学和免疫学在内的各个医学领域显示出有希望的结果。TYK2 是 Janus 激酶 (JAK) 家族成员,在细胞因子信号传导和免疫调节中发挥着重要作用。本专利摘要探讨了 TYK2 抑制剂的最新进展,强调了它们在治疗癌症、斑秃和银屑病关节炎等多种疾病方面的潜力。
更新日期:2024-01-23
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