Wound healing is a complex and iterative process involving myriad cellular and biologic processes that are highly regulated to allow satisfactory repair and regeneration of damaged tissues. This review is intended to be an introductory chapter in a volume focusing on the use of platelet concentrates for tissue regeneration. In order to fully appreciate the clinical utility of these preparations, a sound understanding of the processes and factors involved in soft and hard tissue healing. This encompasses an appreciation of the cellular and biological mediators of both soft and hard tissues in general as well as specific consideration of the periodontal tissues. In light of good advances in this basic knowledge, there have been improvements in clinical strategies and therapeutic management of wound repair and regeneration. The use of platelet concentrates for tissue regeneration offers one such strategy and is based on the principles of cellular and biologic principles of wound repair discussed in this review.

中文翻译：

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软组织和硬组织愈合涉及的生物过程和因素


伤口愈合是一个复杂且反复的过程，涉及无数的细胞和生物过程，这些过程受到高度调节，以实现受损组织的令人满意的修复和再生。本综述旨在成为重点关注血小板浓缩物用于组织再生的卷中的介绍性章节。为了充分理解这些制剂的临床效用，需要充分了解软组织和硬组织愈合所涉及的过程和因素。这包括对软组织和硬组织的细胞和生物介质的总体认识以及对牙周组织的具体考虑。鉴于这一基础知识的良好进展，伤口修复和再生的临床策略和治疗管理已经取得了进步。使用血小板浓缩物进行组织再生提供了一种这样的策略，并且基于本综述中讨论的伤口修复的细胞原理和生物学原理。