Vacuoles in circulating immature myeloid cells in VEXAS syndrome and comparison with UBA1-wild type patients,American Journal of Hematology

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Vacuoles in circulating immature myeloid cells in VEXAS syndrome and comparison with UBA1-wild type patients
American Journal of Hematology ( IF 10.1 ) Pub Date : 2023-12-22 , DOI: 10.1002/ajh.27192
Valentin Lacombe _{1,

2} , Franck Genevieve _{3,

4} , Floris Chabrun _{2,

5}

Affiliation

We did not identify any vacuole-related differences in circulating immature myeloid cells between VEXAS patients and UBA1-WT ‘VEXAS-like’ patients. The similar vacuolization of circulating immature myeloid cells between VEXAS and UBA1-WT patients is explained by the main bloodstream passage of late precursors, in which the vacuolization is already similar in bone marrow in both cases.

中文翻译：

VEXAS 综合征中循环未成熟骨髓细胞中的空泡以及与 UBA1 野生型患者的比较

我们没有发现 VEXAS 患者和 UBA1-WT“VEXAS 样”患者之间循环未成熟骨髓细胞存在任何与液泡相关的差异。 VEXAS 和 UBA1-WT 患者之间循环未成熟骨髓细胞的相似空泡化可以通过晚期前体的主要血流通道来解释，其中两种情况下骨髓中的空泡化已经相似。

更新日期：2023-12-22

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