A boy with known autism spectrum disorder was transferred to our department due to a rapidly worsening respiratory situation. The patient’s history revealed previous treatment with albendazole against a Toxocara infection 2 weeks prior in Poland. Blood analysis showed such severe eosinophilia and markedly elevated levels of IgE that, initially, a hematologic malignancy was suspected. However, diagnostic workup including autoimmune diagnostic, molecular genetic testing, fluorescence in situ hybridization (FISH), bone marrow aspiration, and parasitological testing led to the diagnosis of an insufficiently treated Toxocara infection. Treatment with albendazole and prednisone (six cycles for 4 weeks each) was administered. This treatment regime led to prompt improvement of symptoms and normalization of laboratory findings.

由于呼吸状况迅速恶化，一名患有已知自闭症谱系障碍的男孩被转移到我们部门。患者的病史显示，2 周前在波兰接受过阿苯达唑治疗弓蛔虫感染。血液分析显示嗜酸性粒细胞增多症非常严重，IgE 水平显著升高，因此最初怀疑血液系统恶性肿瘤。然而，包括自身免疫诊断、分子遗传学检测、荧光原位杂交 （FISH）、骨髓穿刺和寄生虫学检测在内的诊断性检查导致诊断为治疗不足的弓蛔虫感染。给予阿苯达唑和泼尼松治疗 （6 个周期，每个周期 4 周）。这种治疗方案导致症状迅速改善，实验室检查结果正常化。