Blomia tropicalis is an allergen-producing mite in the human environment in tropical regions. The microbiome of B. tropicalis was described using the barcode sequencing region of V4 16S rDNA and genome assemblage. Mixta mediterraneensis, previously isolated from human skin swabs, was identified as a B. tropicalis gut symbiont based on genome assembly. The microbiome contains two bacteria, Staphylococcus and M. mediterraneensis. The number of M. mediterraneensis 16S DNA copies was 10⁶ per mite and 10⁹ per feces in the rearing chamber based on qPCR quantification. The profile of this bacterium reached 50% of reads in the mite gut and feces. Genomic analyses revealed that the bacterium has several metabolic pathways that suggest metabolic cooperation with the mite host in vitamin and amino acid synthesis, nitrogen recycling, and antimicrobial defense. Lysozyme is present in the symbiotic bacterium but absent in the mite. The B. tropicalis microbiome contained Staphylococcus, which accelerates mite population growth. Mites can digest Staphylococcus by using specific enzymes with hydrolytic functions against bacterial cell walls (chitinases and cathepsin D), leading to endocytosis of bacteria and their degradation in lysosomes and phagosomes. Gene expression analysis of B. tropicalis indicated that phagocytosis was mediated by the PI3-kinase/Akt pathway interacting with the invasins produced by M. mediterraneensis. Moreover, the symbiont had metabolic pathways that allowed it to recycle the mite metabolic waste product guanine, known as a mite attractant. The mite host symbiont enhances mite aggregation in the feces, and the fecal–oral transmission route is excepted.

热带布洛米亚是热带地区人类环境中产生过敏原的螨虫。使用 V4 16S rDNA 的条形码测序区域和基因组组合描述了热带芽孢杆菌的微生物组。 Mixta mediterraneensis先前从人类皮肤拭子中分离出来，基于基因组组装被鉴定为热带芽孢杆菌肠道共生体。微生物组包含两种细菌：葡萄球菌和地中海分枝杆菌。根据 qPCR 定量，饲养室中地中海分枝杆菌16S DNA 拷贝数为每只螨 10 ⁶个和每粪便 10 ^{9 个}。这种细菌的分布达到了螨虫肠道和粪便中 50% 的读数。基因组分析表明，该细菌具有多种代谢途径，表明其在维生素和氨基酸合成、氮循环和抗菌防御方面与螨宿主进行代谢合作。溶菌酶存在于共生细菌中，但在螨虫中不存在。热带芽孢杆菌微生物组含有葡萄球菌，可加速螨虫种群的增长。螨虫可以通过使用对细菌细胞壁具有水解功能的特定酶（几丁质酶和组织蛋白酶 D）来消化葡萄球菌，导致细菌的内吞作用及其在溶酶体和吞噬体中的降解。热带芽孢杆菌的基因表达分析表明，吞噬作用是由 PI3 激酶/Akt 途径与地中海分支杆菌产生的入侵素相互作用介导的。此外，共生体具有代谢途径，使其能够回收螨虫代谢废物鸟嘌呤（称为螨虫引诱剂）。 螨宿主共生体增强了螨在粪便中的聚集，粪口传播途径除外。