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Anticancer effects of solasonine: Evidence and possible mechanisms
Biomedicine & Pharmacotherapy ( IF 6.9 ) Pub Date : 2024-01-10 , DOI: 10.1016/j.biopha.2024.116146
YingZheng Wang 1 , Tong Wang 2 , WeiDong Liu 1 , GuangZhi Luo 1 , GuangYing Lu 1 , YaNan Zhang 1 , HuaXin Wang 1
Affiliation  

The effectiveness and safety of traditional Chinese medicine's active ingredients in anti-tumor effects have attracted widespread attention worldwide. Solasonine is the main anti-tumor component of the traditional Chinese medicine , which can inhibit tumor cell proliferation, induce apoptosis, induce ferroptosis in tumor cells, and inhibit of tumor cell metastasis, thereby inhibiting tumor progression. Therefore, we summarized anti-tumor mechanisms and targets of solasonine to provide new ideas and theoretical basis for its further development and application.

中文翻译:


茄碱的抗癌作用:证据和可能的机制



中药活性成分抗肿瘤作用的有效性和安全性引起了世界范围内的广泛关注。茄碱是中药的主要抗肿瘤成分,可抑制肿瘤细胞增殖、诱导细胞凋亡、诱导肿瘤细胞铁死亡、抑制肿瘤细胞转移,从而抑制肿瘤进展。因此,我们总结了茄碱的抗肿瘤机制和作用靶点,为其进一步开发和应用提供新的思路和理论依据。
更新日期:2024-01-10
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