A new class of macrocyclic peptides,Nature Chemical Biology

当前位置： X-MOL 学术 › Nat. Chem. Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A new class of macrocyclic peptides
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-01-08 , DOI: 10.1038/s41589-023-01507-y
Krushnamurthy Pattanayakanahalli Henjarappa ₁ , Simita Das ₁ , Nilkamal Mahanta ₁

Affiliation

Nature has evolved elegant enzymatic strategies to cyclize peptides, resulting in complex macrocyclic compounds with potent biological activities. A study illustrates the diverse chemical versatility of one such remarkable enzyme family, the cytochrome P450 macrocyclases, which form new biaryl crosslinks in ribosomal peptidic natural products.

中文翻译：