Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy ( IF 4.3 ) Pub Date : 2024-01-02 , DOI: 10.1016/j.saa.2024.123835 Ting-Ting Zhang 1 , Yun Lu 1 , Ji-Hong Lu 1 , An-Ting Zhao 1 , Carl Redshaw 2 , Xin Xiao 1
pH plays a crucial part in numerous chemical and physiological processes. In this work, a new perylene diimide derivative that acts as a pH-sensitive dye with Bay Area Carboxylic Acid functionality. The derivative utilizes the outstanding thermal, chemical and photochemical stability found in PDI materials and has remarkable UV–visible absorption and fluorescence emission qualities. Based on these properties, a fluorescent probe (PCA) was synthesised using a perylene tetracarbodiimide (PDI) backbone for the recognition of alkaline pH. In alkaline environments where the pH values are between 10 and 14, the fluorescence intensity significantly decreases, and a blue shift occurs, which is a standard feature of alkaline pH probes. The probe demonstrates exceptional sensing ability within the pH range of 10.00–14.00, with notable stability and reversibility. Encapsulation of the probe in a thin polymer film material enhances the pH sensing capability of the system. New sensor has been developed to detect basic amino acids by utilizing the probes' pH response characteristics. this sensor has also been applied to detect the concentration of arginine.
中文翻译:
使用苝胺衍生探针在高碱性条件下检测碱性氨基酸
pH 在许多化学和生理过程中起着至关重要的作用。在这项工作中,一种新型苝二酰亚胺衍生物可作为具有湾区羧酸功能的 pH 敏感染料。该衍生物利用了 PDI 材料中出色的热稳定性、化学稳定性和光化学稳定性,并具有卓越的紫外-可见光吸收和荧光发射质量。基于这些特性,使用苝四碳二亚胺 (PDI) 主链合成了荧光探针 (PCA),用于识别碱性 pH 值。在pH值在10至14之间的碱性环境中,荧光强度显着降低,并发生蓝移,这是碱性pH探针的标准特征。该探针在 10.00–14.00 pH 范围内表现出卓越的传感能力,具有显着的稳定性和可逆性。将探针封装在聚合物薄膜材料中增强了系统的 pH 传感能力。新型传感器已被开发出来,利用探针的 pH 响应特性来检测碱性氨基酸。该传感器还被应用于检测精氨酸的浓度。