Electrospinning technology has garnered wide attention over the past few decades in various biomedical applications including drug delivery, cell therapy, and tissue engineering. This technology can create nanofibers with tunable fiber diameters and functionalities. However, the 2D membrane nature of the nanofibers, as well as the rigidity and low porosity of electrospun fibers, lower their efficacy in tissue repair and regeneration. Recently, new avenues have been explored to resolve the challenges associated with 2D electrospun nanofiber membranes. This review discusses recent trends in creating different electrospun nanofiber microstructures from 2D nanofiber membranes by using various post-processing methods, as well as their biotechnological applications.

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用于生物技术用途的电纺纳米纤维材料设计的新维度

过去几十年来，静电纺丝技术在药物输送、细胞治疗和组织工程等各种生物医学应用中引起了广泛关注。该技术可以制造具有可调纤维直径和功能的纳米纤维。然而，纳米纤维的二维膜性质以及电纺纤维的刚性和低孔隙率降低了其组织修复和再生的功效。最近，人们探索了新的途径来解决与二维电纺纳米纤维膜相关的挑战。本综述讨论了通过使用各种后处理方法从二维纳米纤维膜创建不同静电纺丝纳米纤维微结构的最新趋势及其生物技术应用。