当前位置: X-MOL 学术Artif. Organs › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Investigation of the role of von Willebrand factor in shear-induced platelet activation and functional alteration under high non-physiological shear stress
Artificial Organs ( IF 2.2 ) Pub Date : 2023-12-19 , DOI: 10.1111/aor.14698
Dong Han 1 , Wenji Sun 1 , Kiersten P Clark 1 , Bartley P Griffith 1 , Zhongjun J Wu 1, 2
Affiliation  

von Willebrand factor (vWF) plays a crucial role in physiological hemostasis through platelet and subendothelial collagen adhesion. However, its role in shear-induced platelet activation and functional alteration under non-physiological conditions common to blood-contacting medical devices (BCMDs) is not well investigated.

中文翻译:


高非生理剪切应力下冯维勒布兰德因子在剪切诱导血小板活化和功能改变中的作用的研究



血管性血友病因子(vWF)通过血小板和内皮下胶原蛋白粘附在生理止血中发挥着至关重要的作用。然而,其在血液接触医疗器械 (BCMD) 常见的非生理条件下剪切诱导的血小板活化和功能改变中的作用尚未得到充分研究。
更新日期:2023-12-19
down
wechat
bug