Non-selective β-blockers (NSBBs) and endoscopic variceal-ligation (EVL) have similar efficacy preventing first variceal bleeding. Compensated and decompensated cirrhosis are markedly different stages, which may impact treatment outcomes. We aimed to assess the efficacy of NSBBs vs EVL on survival in patients with high-risk varices without previous bleeding, stratifying risk according to compensated/decompensated stage of cirrhosis.

中文翻译：

---

通过根据肝硬化的临床阶段调整治疗来改善静脉曲张出血的一级预防。个体参与者数据的竞争风险荟萃分析


非选择性β受体阻滞剂（NSBB）和内镜下静脉曲张结扎术（EVL）在预防首次静脉曲张出血方面具有相似的功效。代偿期和失代偿期肝硬化处于明显不同的阶段，这可能会影响治疗结果。我们的目的是评估 NSBB 与 EVL 对既往无出血的高风险静脉曲张患者生存的疗效，根据肝硬化代偿/失代偿阶段对风险进行分层。